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In Immunology and Dermatology, Pharmaceuticals is working to expand the indications for Cosentyx beyond psoriasis, with pivotal Phase III studies in psoriatic arthritis (FUTURE 1 and 2) and ankylosing spondylitis (MEASURE 1 and 2) forming the basis for regulatory filings, including in the US and EU, which were completed for both indications in the second quarter of 2015.

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Growth Products" are an indicator of the rejuvenation of the portfolio, and comprise products launched in a key market (EU, US, Japan) in 2011 or later, or products with exclusivity in key markets until at least 2020 (except Sandoz, which includes only products launched in the last 24 months).

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Sponsors' use of the new US biosimilars pathway will depend on the degree to which FDA is driven by this scientific justification for an abbreviated clinical development program, as opposed to their endorsement of a precautionary approach that requires many of the typical development steps of a the traditional novel biologic 351(a) biologics license application.

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