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Comparison with other studiesPrevious studies examining the association between levothyroxine replacement and fracture risk have yielded inconsistent conclusions and have not tackled the role of levothyroxine dose in this relation.

The Antenatal Thyroid Screening and Childhood Cognitive Function study (CATS) was a prospective, randomized, multicenter trial that involved almost 22 000 women who were screened for thyroid disease within the first 16 weeks of gestation by means of TSH and FT 4 measurements ().

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