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In cardiac uses, it works as a nonselective muscarinic acetylcholinergic antagonist, increasing firing of the sinoatrial node (SA) and conduction through the atrioventricular node (AV) of the heart, opposes the actions of the vagus nerve, blocks acetylcholine receptor sites, and decreases bronchial secretions.
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Administration. Rifaximin tablets may be taken with or without food. Extemporaneous 20 mg/ml rifaximin oral suspension: With a mortar and pestle, crush six 200 mg rifaximin tablets into a fine powder.